Tags: Disease.
X-linked ichthyosis (XLI) (also known as Steroid sulfatase deficiency and X-linked recessive ichthyosis)(from the Ancient Greek ‘ichthys’ meaning ‘fish’) is a skin condition caused by the hereditary deficiency of the steroid sulfatase (STS) enzyme that affects 1 in 2000 to 1 in 6000 males. XLI manifests with dry scaly skin and is due to deletions or mutations in the STS gene. XLI can also occur in the context of larger deletions causing contiguous gene syndromes.
