Tags: Disease.
Wolman disease (also known as Wolman’s disease or early onset lysosomal acid lipase deficiency is a rare genetic disorder caused by a deficiency of an enzyme known as lysosomal acid lipase (LAL or LIPA). This enzyme is necessary to break down certain lipids inside the cells. Deficiency of the LAL/LIPA enzyme causes a build-up of fat in the liver gut and other parts of the body. Wolman disease belongs to a group of diseases known as lysosomal storage disorders (LSDs).
