Tags: Drug.
WAY-317538 (SEN-12333) is a drug that acts as a potent and selective full agonist for the α7 subtype of neural nicotinic acetylcholine receptors. It was not the most potent compound in the series but was selected for further development on the basis of its high selectivity over related receptors ease of synthesis and good in vivo properties including high oral bioavailability and good brain penetration.