Tags: Chemical Compound, Chemical Substance.
WAY-161503 is a full agonist at the serotonin 5-HT2B and 5-HT2C receptors. Administration of WAY-161503 decreased food intake in rats an effect mediated by its action on the 5-HT2C receptors. In addition there was no development of tolerance with up to 15 days of treatment. However clinical utility of WAY-161503 may be limited as activation of the 5-HT2B receptor has been linked to pulmonary hypertension and cardiac valve problems.
