Tags: Enzyme.
Vitamin D3 24-hydroxylase (EC 1.14.13.126 CYP24A1) is an enzyme with system name calcitriolNADPH:oxygen oxidoreductase (24-hydroxylating). This enzyme catalyses the following chemical reaction (1) calcitriol + NADPH + H+ + O2 calcitetrol + NADP+ + H2O (2) calcidiol + NADPH + H+ + O2 secalciferol + NADP+ + H2OVitamin D3 24-hydroxylase is a heme-thiolate enzyme (P-450).