Tags: Chemical Compound, Chemical Substance.
Vanillotoxins (VaTxs subtypes VaTx1 VaTx2 and VaTx3) are neurotoxins found in the venom of the tarantula Psalmopoeus cambridgei. They act as agonists for the transient receptor potential cation channel subfamily V member 1 (TRPV1) activating the pain sensory system. VaTx1 and 2 also act as antagonists for the Kv2-type voltage-gated potassium channel (Kv2) inducing paralytic behavior in small animals.
