The Vanderbilt Theatre was a New York City Broadway theatre designed by architect Eugene De Rosa for producer Lyle Andrews. It opened in 1918 located at 148 West 48th Street. The theatre was demolished in 1954.The 780-seat theatre hosted the long-running musical Irene from 1919 to 1921. In the mid-1920s several Rodgers and Hart musicals played at the theatre. Andrews lost the theatre during the Great Depression and in 1931 it was briefly renamed the Tobis to show German films.
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