Tags: Chemical Compound, Chemical Substance.
Urotensin-II (U-II) is a peptide ligand initially isolated from the neurosecretory system of the Goby fish (Gillichthys mirabilis). For many years it was thought that U-II does not exhibit significant effects in mammalian systems; a view quickly overturned when it was demonstrated that Goby U-II produces slow relaxation of mouse anococcygeus muscle in addition to contraction of rat artery segments.
