Tags: Protein.
Nucleolar transcription factor 1 is a protein that in humans is encoded by the UBTF gene.Upstream binding factor (UBF) is a transcription factor required for expression of the 18S 5.8S and 28S ribosomal RNAs along with SL1 (a complex of TBP (MIM 600075) and three TBP-associated factors or ‘TAFs’). Two UBF polypeptides of 94 and 97 kD exist in the human (Bell et al. 1988). UBF is a nucleolar phosphoprotein with both DNA binding and transactivation domains.