Tags: Protein.
In molecular biology Type I topoisomerases are enzymes that cut one strand of double-stranded DNA relax the strand and reanneal the strands. They are further subdivided into two structurally and mechanistically distinct topoisomerases: type IA and type IB. Type IA topoisomerases change the linking number of a circular DNA strand by units of strictly 1. Type IB topoisomerases change the linking number by multiples of 1 (n).
