Tags: Protein.
Thioredoxin reductase 1 cytoplasmic is an enzyme that in humans is encoded by the TXNRD1 gene.This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity.