Tags: Drug.

Turosteride (FCE-26073) is a selective inhibitor of the enzyme 5α-reductase which was under investigation by GlaxoSmithKline for the treatment of benign prostatic hyperplasia (BPH) but was never marketed. Similarly to finasteride turosteride is selective for the type II isoform of 5α-redcutase with about 15-fold selectivity for it over type I isoform of the enzyme. In animal studies it has been shown to inhibit prostate size and retard tumor growth.

Turosteride_structure.png
ATC prefix
none
CAS number
137099-09-3
FDA UNII code
LU1LTK666W
IUPAC name
(4aR4bS6aS7S9aS9bS11aR)-14a6a-trimethyl-2-oxo-N-(propan-2-yl)-N-(propan-2-ylcarbamoyl)hexadecahydro-1H-indeno[54-f]quinoline-7-carboxamide)
PubChem
65986

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