Tags: Protein.
GDP-L-fucose synthetase is an enzyme that in humans is encoded by the TSTA3 gene.Tissue specific transplantation antigen P35B is a NADP(H)-binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates including blood group ABH antigens and developmental adhesion antigens.