Tags: Protein.
Tumor susceptibility gene 101 also known as TSG101 is a human gene that encodes for a cellular protein of the same name.The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator.