Tags: Enzyme.
Tryptophan hydroxylase (TPH) is an enzyme (EC 1.14.16.4) involved in the synthesis of the neurotransmitter serotonin. TPH catalyzes the following chemical reaction L-tryptophan + tetrahydrobiopterin + O2 5-Hydroxytryptophan + dihydrobiopterin + H2OIt employs one additional cofactor iron.