Tags: Enzyme.
TRNAHis guanylyltransferase (EC 2.7.7.79 histidine tRNA guanylyltransferase Thg1p Thg1) is an enzyme with system name p-tRNAHis:GTP guanylyltransferase (ATP-hydrolysing). This enzyme catalyses the following chemical reaction p-tRNAHis + ATP + GTP pppGp-tRNAHis + AMP + diphosphate (overall reaction) (1a) p-tRNAHis + ATP App-tRNAHis + diphosphate (1b) App-tRNAHis + GTP pppGp-tRNAHis + AMPThe enzyme requires a divalent cation for activity.