Tags: Enzyme.
TRNA (guanine26-N2)-dimethyltransferase (EC 2.1.1.216 Trm1p TRM1 tRNA (m22G26)dimethyltransferase) is an enzyme with system name S-adenosyl-L-methionine:tRNA (guanine26-N2)-dimethyltransferase. This enzyme catalyses the following chemical reaction 2 S-adenosyl-L-methionine + guanine26 in tRNA 2 S-adenosyl-L-homocysteine + N2-dimethylguanine26 in tRNAThe enzyme dissociates from its tRNA substrate between the two consecutive methylation reactions.