Tags: Chemical Compound, Chemical Substance.
Triacsin C is a potent inhibitor of long fatty acyl CoA synthetase. It blocks β-cell apoptosis induced by fatty acids (lipoapoptosis) in a rat model of obesity. In addition it blocks the de novo synthesis of triglycerides diglycerides and cholesterol esters thus interfering with lipid metabolism.In addition triacsin C is a potent vasodilator.Inhibition of lipid metabolism reduces/removes lipid droplets from HuH7 cells.
