Tags: Protein.
In molecular biology the transcriptional activator LAG-3 is a transcriptional activator protein. The C. elegans Notch pathway involved in the control of growth differentiation and patterning in animal development relies on either of the receptors GLP-1 or LIN-12. Both these receptors promote signalling by the recruitment of LAG-3 to target promoters where it then acts as a transcriptional activator. LAG-3 works as a ternary complex together with the DNA binding protein LAG-1.
