Tags: Protein.
TNF receptor-associated factor 1 is a protein that in humans is encoded by the TRAF1 gene.The protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB.