Tags: Drug.
Tipepidine was discovered in the 1950s. Under the trade-names (Bithiodine Sotal Antupex Asverin) is used as a centrally-acting cough suppressant of the opioid type. It is a member of the thiambutene series of open-chain (methadone-related) synthetic opioids which include Ohton (dimethylthiambutene) a strong narcotic analgesic used particularly in veterinary medicine in Japan and other East Asian countries. It was developed in Japan in 1959 and is used as the citrate and hibenzate salts.