Tags: Chemical Compound, Chemical Substance.
Thiouracil refers both to a specific molecule consisting of a sulfated uracil and a family of molecules based upon that structure. The substance is a historically relevant antithyroid preparation. Astwood E.B. used it in 1943 as therapy of Graves’ disease for the first time. It remains in use.Thiouracil inhibits thyroid activity by blocking the enzyme thyroid peroxidase.
