Tags: Protein.
Tetraspanins are a family of membrane proteins found in all multicellular eukaryotes.Tetraspanins also called tetraspans or the transmembrane 4 superfamily (TM4SF) have four transmembrane domains intracellular N- and C-termini and two extracellular domains one short (called the small extracellular domain or loop SED/SEL or EC1) and one longer typically 100 amino acid residues (the large extracellular domain/loop LED/LEL or EC2).