Tags: Chemical Compound, Chemical Substance.
Taxadiene (taxa-411-diene) is a diterpene. Taxadiene is the first committed intermediate in the synthesis of taxol.Enzymatically taxadiene is produced from geranylgeranyl pyrophosphate by taxadiene synthase.A biochemical kilogram-scale production of taxadiene has been reported using genetically engineered Escherichia coli. Six hydroxylation reactions and a few others are needed to convert taxadiene to baccatin III.
