Tags: Chemical Compound, Chemical Substance.
Tamibarotene (brand name: Amnolake) also called retinobenzoic acid is orally active synthetic retinoid developed to overcome all-trans retinoic acid (ATRA) resistance with potential antineoplastic activity against acute promyelocytic leukaemia (APL) . It is currently marketed only in Japan and early trials have demonstrated that it tends to be better tolerated than ATRA. It has also been investigated as a possible treatment for Alzheimer’s disease multiple myeloma and Crohn’s disease.