Tags: Drug.

Tacrolimus (also FK-506 or fujimycin trade names Prograf Advagraf Protopic) is an immunosuppressive drug that is used mainly after allogeneic organ transplant to reduce the activity of the patient’s immune system and so lower the risk of organ rejection.

Tacrolimus2DCSD.svg
ATC prefix
D11
ATC suffix
AH01
Bioavailability
20.0
CAS number
104987-11-3
DrugBank
DB00864
FDA UNII code
Y5L2157C4J
IUPAC name
-hexadecahydro-5 19-dihydroxy, -tetrone monohydrate, ]-1-methylethenyl]-1416-dimethoxy, -3-[2-(4-hydroxy-3-methoxycyclohexyl), -4101218-tetramethyl-8-(2-propenyl), -56811121314151617181924252626a, 3S-[3R*[E(1S*3S*4S*)], -1519-epoxy-3H-pyrido[21-c] [14] oxaazacyclotricosine-172021(4H23H), 4S*5R*8S*9E12R*14R*15S*16R*18S*19S*26aR*
PubChem
6473866

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