Tags: Disease.
Superior vena cava syndrome (SVCS) or superior vena cava obstruction (SVCO) is usually the result of the direct obstruction of the superior vena cava by malignancies such as compression of the vessel wall by right upper lobe tumors or thymoma and/or mediastinal lymphadenopathy. The most common malignancy that causes SVCS is bronchogenic carcinoma. Cerebral edema is rare but if it occurs it may be fatal.