Tags: Protein.
Sulfatase-modifying factor 2 is an enzyme that in humans is encoded by the SUMF2 gene.The catalytic sites of sulfatases are only active if they contain a unique amino acid C-alpha-formylglycine (FGly). The FGly residue is posttranslationally generated from a cysteine by enzymes with FGly-generating activity. The gene described in this record is a member of the sulfatase-modifying factor family and encodes a protein with a DUF323 domain that localizes to the lumen of the endoplasmic reticulum.