Sulfamethoxazole (abbreviated SMZ or SMX) is a sulfonamide bacteriostatic antibiotic.It is most often used as part of a synergistic combination with trimethoprim in a 5:1 ratio in co-trimoxazole (abbreviated SMZ-TMP and SMX-TMP or TMP-SMZ and TMP-SMX) also known under trade names such as Bactrim Septrin or Septra; in Eastern Europe it is marketed as Biseptol.
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