Tags: Protein.
Stromal interaction molecule 1 is a protein that in humans is encoded by the STIM1 gene. STIM1 has a single transmembrane domain and is localized to the endoplasmic reticulum and to a lesser extent to the plasma membrane.Even though the protein has been identified earlier its function was unknown until recently. In 2005 it was discovered that STIM1 functions as a calcium sensor in the endoplasmic reticulum.