ABCG5 and ABCG8 genes encode for two proteins sterolin-1 and -2 respectively. Sterolin-1 and –2 are two ‘half’ adenosine triphosphate binding (ATP) cassette (ABC) transporters which found to be indispensable for the regulation of sterol absorption and excretion. Mutations in either genes result in a lipid disorder sitosterolemia.
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