Tags: Protein.

Sterol Regulatory Element-Binding Proteins (SREBPs) are transcription factors that bind to the sterol regulatory element DNA sequence TCACNCCAC. Mammalian SREBPs are encoded by the genes SREBF1 and SREBF2. SREBPs belong to the basic-helix-loop-helix leucine zipper class of transcription factors. Unactivated SREBPs are attached to the nuclear envelope and endoplasmic reticulum membranes.

Sterol_Regulatory_Element_Binding_Protein_1A.png
arm
p, q
band
13, 11.2
chromosome
22, 17
EntrezGene
6720, 6721
HGNCid
11290, 11289
OMIM id
184756, 600481
PDB
1am9
RefSeq
NM_004176, NM_004599
symbol
SREBF1, SREBF2
UniProt
P36956, Q12772

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