Signal Transducer and Activator of Transcription 5 refers to two highly related proteins STAT5A and STAT5B which are part of the seven-membered STAT family of proteins. Though STAT5A and STAT5B are encoded by separate genes the proteins are 90% identical at the amino acid level. STAT5 proteins are involved in cytosolic signalling and in mediating the expression of specific genes.
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