Tags: Drug.
ST-1936 (2-Methyl-5-chloro-NN-dimethyltryptamine) is a tryptamine derivative which is used in scientific research. It acts as a selective 5-HT6 receptor agonist with a Ki of 13 nM and much weaker action at 5-HT2B and 5-HT7 subtypes. In animal studies it has been found to increase dopamine and noradrenaline mediated signalling but decreases glutamatergic transmission and has antidepressant effects.