Tags: Enzyme.
Spore photoproduct lyase (EC 4.1.99.14 SAM SP lyase SPL SplB SplG) is a radical SAM enzyme that repairs a particular kind of lesion that arises upon UV-radiation of bacterial DNA. This repair mechanism is one of the reasons for the resilience of certain bacterial spores. Through a series of radical reactions the photodimer 3 5-thyminyl-56-dihydrothymine is disconnected to give back two functional thymine rings.
