Tags: Biological Database, Database.
SPIKE (Signaling Pathways Integrated Knowledge Engine) is a database of highly curated interactions for particular human pathways. SPIKE was developed by Ron Shamir’s computational biology group in cooperation with the group of Yosef Shiloh an Israel Prize recipient for his research in systems biology and the group of Karen B. Avraham a leading researcher of human deafness all from Tel-Aviv University.