Tags: Protein.
Sphingosine kinase 1 is an enzyme that in humans is encoded by the SPHK1 gene.Sphingosine kinase 1 phosphorylates sphingosine to sphingosine-1-phosphate (S1P) SK1 is normally a cytosolic protein but is recruited to membranes rich in phosphatidate (PA) a product of Phospholipase D (PLD)Sphingosine-1-phosphate (SPP) is a novel lipid messenger with both intracellular and extracellular functions.