Tags: Enzyme.
Sphingomyelin phosphodiesterase (EC 3.1.4.12 neutral sphingomyelinase sphingomyelinase SMase) is a hydrolase enzyme that is involved in sphingolipid metabolism reactions. SMase is a member of the DNase I superfamily of enzymes and is responsible for breaking sphingomyelin (SM) down into phosphocholine and ceramide. The activation of SMase has been suggested as a major route for the production of ceramide in response to cellular stresses.
