Tags: Drug.
Sparteine is a class 1a antiarrhythmic agent; a sodium channel blocker. It is an alkaloid and can be extracted from scotch broom. It is the predominant alkaloid in Lupinus mutabilis and is thought to chelate the bivalents calcium and magnesium. It is not FDA approved for human use as an antiarrhythmic agent and it is not included in the Vaughn Williams classification of antiarrhythmic drugs.It is also used as a chiral base in organic chemistry and as a ligand in organic chemical synthesis.
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