Tags: Drug.

Sofosbuvir (brand name Sovaldi) is a drug used for hepatitis C infection with a high cure rate. It inhibits the RNA polymerase that the hepatitis C virus (HCV) uses to replicate its RNA. It was discovered at Pharmasset and developed by Gilead Sciences.Sofosbuvir is a component of the first all-oral interferon-free regimen approved for treating chronic hepatitis C.

Sofosbuvir_structure.svg
ATC prefix
J05
ATC suffix
AB
CAS number
1190307-88-0
FDA UNII code
WJ6CA3ZU8B
IUPAC name
Isopropyl (2S)-2-[(2R3R4R5R)-5-(24-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyl-tetrahydrofuran-2-yl]methoxy-phenoxy-phosphoryl]amino]propanoate
PubChem
45375808

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