Tags: Protein.
Sorting nexin-5 is a protein that in humans is encoded by the SNX5 gene.This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain which is a phosphoinositide binding domain and are involved in intracellular trafficking. This protein is a component of the mammalian retromer complex which facilitates cargo retrieval from endosomes to the trans-Golgi network. It has also been shown to bind to the Fanconi anemia complementation group A protein.