Sir Thomas Myddelton 2nd Baronet (ca. 1651 – 5 February 1684) was a Welsh politician who sat in the House of Commons between 1679 and 1681.Myddelton was the son of Sir Thomas Myddelton 1st Baronet of Chirk Castle and his first wife Mary Cholmondley daughter of Thomas Cholmondley of Vale Royal Cheshire.