Tags: Protein.
Nucleotide exchange factor SIL1 is a protein that in humans is encoded by the SIL1 gene.This gene encodes a resident endoplasmic reticulum (ER) N-linked glycoprotein with an N-terminal ER targeting sequence 2 putative N-glycosylation sites and a C-terminal ER retention signal. This protein functions as a nucleotide exchange factor for another unfolded protein response protein. Mutations in this gene have been associated with Marinesco-Sjogren syndrome.