Tags: Disease.
Sickle-cell disease (SCD) or sickle-cell anaemia (SCA) or drepanocytosis is a hereditary blood disorder characterized by red blood cells that assume an abnormal rigid sickle shape. Sickling decreases the cells’ flexibility and results in a risk of various life-threatening complications. This sickling occurs because of a mutation in the haemoglobin gene. Individuals with one copy of the mutant gene display both normal and abnormal haemoglobin.