Tags: Drug.
SH-053-R-CH3-2′F is a drug used in scientific research which is a benzodiazepine derivative. It produces some of the same effects as other benzodiazepines but is much more subtype-selective than most other drugs of this class having high selectivity binding affinity and efficacy at the α5 subtype of the GABAA receptor. This gives much tighter control of the effects produced and so while SH-053-R-CH3-2′F retains sedative and anxiolytic effects it does not cause ataxia at moderate doses.