Tags: Enzyme.

Sepiapterin reductase (L-threo-78-dihydrobiopterin forming) (EC 1.1.1.325) is an enzyme with system name L-threo-78-dihydrobiopterin:NADP+ oxidoreductase. This enzyme catalyses the following chemical reaction (1) L-threo-78-dihydrobiopterin + NADP+ sepiapterin + NADPH + H+ (2) L-threo-tetrahydrobiopterin + 2 NADP+ 6-pyruvoyl-5678-tetrahydropterin + 2 NADPH + 2 H+This bacterial (Chlorobium tepidum) enzyme catalyses the final step in the de novo synthesis of tetrahydrobiopterin from GTP.

EC number
1.1.1.325

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