Tags: Protein.
Sentrin-specific protease 8 is an enzyme that in humans is encoded by the SENP8 gene.NEDD8 (MIM 603171) is a ubiquitin-like protein that becomes conjugated to the cullin (see CUL1; MIM 603134) subunit of several ubiquitin ligases. This conjugation called neddylation is required for optimal ubiquitin ligase activity.