Tags: Disease.
Scleromyositis or the PM/Scl overlap syndrome is a complex autoimmune disease (a disease in which the immune system attacks the body). Patients with scleromyositis have symptoms of both systemic scleroderma and either polymyositis or dermatomyositis and is therefore considered an overlap syndrome. Although it is a rare disease it is one of the more common overlap syndromes seen in scleroderma patients together with MCTD and Antisynthetase syndrome.