Tags: Drug.
SB-271046 is a drug which is used in scientific research. It was one of the first selective 5-HT6 receptor antagonists to be discovered and was found through high-throughput screening of the SmithKline Beecham Compound Bank using cloned 5-HT6 receptors as a target with an initial lead compound being developed into SB-271046 through a structure-activity relationship (SAR) study.