Tags: Drug.
Sapacitabine is a drug undergoing research for potential use in chemotherapy.Sapacitabine is an oral nucleoside analog prodrug that acts through a dual mechanism. The compound interferes with DNA synthesis by causing single-strand DNA breaks and induces arrest of the cell division cycle at G2 phase.Both sapacitabine and its major metabolite CNDAC have demonstrated potent anti-tumor activity in both blood and solid tumors in preclinical studies.
